The updated IISinformaiton.com site is now running wordpress on IIS. The team tested a few blog systems and landed on WordPress as the final choice. During our process we have followed a few guides and also learned a few things.
Here are a few good instructions for installing wordpress on IIS:
Instructions for using the Web Application Installer : http://blogs.iis.net/richma/archive/2009/12/30/installing-word-press-on-iis-using-the-web-platform-installer-webpi.aspx
Installing manually without the WAI: http://learn.iis.net/page.aspx/280/install-wordpress-on-iis/
Detailed install on IIS7: http://www.trainsignaltraining.com/installing-wordpress-on-iis7/2008-10-06/
Some of the key elements to watch for are correctly setting up web permissions and MySQL permissions. Thankfully the team here has used MySQL and WordPress in the past.